Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.3
USERS' SCORE
Moderately Good
Based on 16 Reviews
7.9
Supplement Facts
Serving Size: 2 Enteric Coated Softgels
Amount Per Serving
%DV
Calories
25
Total Fat
2.5 g
4%†
Cholesterol
<5 mg
2%†
Pure+™ Wild Fish Oil ConcentrateYielding: EPA (eicosapentaenoic acid)DHA (docosahexaenoic acid)
2,000 mg700 mg500 mg
******
Polyphen-Oil™ Olive extract (fruit and leaf)[providing 19.5 mg polyphenols, 5.2 mg hydroxytyrosol/tyrosol, 4.4 mg verbascoside/oleuropein]
300 mg
**
Sesame seed lignan extract
10 mg
**
Top Medical Research Studies
9
We conducted a comprehensive trial to understand how different types of omega-3 fatty acids affect cholesterol levels and inflammation in adults struggling with high cholesterol.
Over 12 weeks, participants took various doses of omega-3s, including EPA and DHA, revealing notable benefits. Those receiving higher doses of EPA and DHA saw their triglycerides drop significantly—by up to 15.78%—compared to controls.
Interestingly, ALA supplementation did not lead to improvements in cholesterol or inflammation status, highlighting the superior role of EPA and DHA in managing these health issues.
Over 12 weeks, participants took various doses of omega-3s, including EPA and DHA, revealing notable benefits. Those receiving higher doses of EPA and DHA saw their triglycerides drop significantly—by up to 15.78%—compared to controls.
Interestingly, ALA supplementation did not lead to improvements in cholesterol or inflammation status, highlighting the superior role of EPA and DHA in managing these health issues.
Read More
9
Scallop oil significantly reduces cholesterol
We investigated how different oils, including newly produced scallop oil, fish oil, and krill oil, impact cholesterol levels in obese type II diabetic mice. Our study involved feeding these groups various high-fat diets for 42 days.
Remarkably, the scallop oil group showed a significant reduction in cholesterol levels in both serum and liver, while the fish oil and krill oil groups did not exhibit such benefits. The findings suggest that scallop oil might be a promising option for managing cholesterol and preventing related health issues.
Remarkably, the scallop oil group showed a significant reduction in cholesterol levels in both serum and liver, while the fish oil and krill oil groups did not exhibit such benefits. The findings suggest that scallop oil might be a promising option for managing cholesterol and preventing related health issues.
Read More
9
We examined how swapping a saturated fat diet for omega-3 polyunsaturated fatty acids (n-3PUFAs) affects cholesterol and bone health in hypercholesterolemic rats.
In our study, rats that shifted to an n-3PUFA diet saw a notable decrease in serum lipids. While the diet appeared to positively impact their bone loss linked to periodontitis, rats on the n-3PUFA diet showed results similar to those on a commercial diet, indicating no major advantage of fish oil over a balanced diet.
Overall, our findings suggest that while omega-3s can help with cholesterol, they don't offer significant improvements over typical diets in these conditions.
In our study, rats that shifted to an n-3PUFA diet saw a notable decrease in serum lipids. While the diet appeared to positively impact their bone loss linked to periodontitis, rats on the n-3PUFA diet showed results similar to those on a commercial diet, indicating no major advantage of fish oil over a balanced diet.
Overall, our findings suggest that while omega-3s can help with cholesterol, they don't offer significant improvements over typical diets in these conditions.
Read More
Most Useful Reviews
7.5
Family health boost
321 people found this helpful
Excellent! Omega 3 lowers cholesterol levels, reduces inflammation and improves skin and hair quality. The taste of fish is noticeable, but the quality and composition are excellent, as is the dosage. Although the price has increased due to dollar surges, prioritising health is essential. It's suitable for the whole family, with ample packaging for everyone.
Read More
9
Lower bad cholesterol
19 people found this helpful
Beneficial Supplement: Helps lower bad cholesterol levels. This jar contains an excellent concentration of EPA and DHA – the reason for taking Omega 3.
Read More
9
Great omega choice
3 people found this helpful
The best omega 3 I've tried. This one outperforms others, leaving no fishy taste. It also lowers cholesterol effectively. A brilliant product!
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.3
- All Researches
9
We aimed to understand how Antarctic krill oil (ESKO) affects cholesterol levels, particularly in relation to obesity. Through our study involving mice, we observed that ESKO helped reduce oxidative stress and improve cholesterol metabolism.
While a high-fat diet usually worsens cholesterol levels, ESKO demonstrated a protective effect by reducing fat accumulation and promoting better metabolic health. This suggests that krill oil could be a promising option for managing high cholesterol and obesity-related issues.
While a high-fat diet usually worsens cholesterol levels, ESKO demonstrated a protective effect by reducing fat accumulation and promoting better metabolic health. This suggests that krill oil could be a promising option for managing high cholesterol and obesity-related issues.
Read More
9
CA-rich fish oils lower cholesterol
We investigated whether cetoleic acid (CA), a healthy fat found in certain fish, can help lower cholesterol levels in rodents. Our systematic review included 12 studies, assessing how CA-rich fish oils influenced total cholesterol compared to regular diets.
The results showed a significant reduction in cholesterol levels in rodents that consumed CA-rich oils. However, it’s important to note that the risk of bias in the studies varied, making our conclusions tentative. Overall, these findings suggest CA-rich fish oils could play a beneficial role in heart health, but further research in humans is needed.
The results showed a significant reduction in cholesterol levels in rodents that consumed CA-rich oils. However, it’s important to note that the risk of bias in the studies varied, making our conclusions tentative. Overall, these findings suggest CA-rich fish oils could play a beneficial role in heart health, but further research in humans is needed.
Read More
9
Scallop oil significantly reduces cholesterol
We investigated how different oils, including newly produced scallop oil, fish oil, and krill oil, impact cholesterol levels in obese type II diabetic mice. Our study involved feeding these groups various high-fat diets for 42 days.
Remarkably, the scallop oil group showed a significant reduction in cholesterol levels in both serum and liver, while the fish oil and krill oil groups did not exhibit such benefits. The findings suggest that scallop oil might be a promising option for managing cholesterol and preventing related health issues.
Remarkably, the scallop oil group showed a significant reduction in cholesterol levels in both serum and liver, while the fish oil and krill oil groups did not exhibit such benefits. The findings suggest that scallop oil might be a promising option for managing cholesterol and preventing related health issues.
Read More
9
We examined the role of eicosapentaenoic acid (EPA), specifically icosapent ethyl, in reducing cardiovascular disease risks. Approved by the FDA, this omega-3 treatment showed a notable 25% reduction in major heart events for high-risk patients. These patients already had controlled cholesterol but elevated triglyceride levels.
Importantly, while EPA proved effective, mixed omega-3 products lacking substantial evidence for heart health did not provide the same benefits. We believe adding EPA-only formulations to cardiovascular prevention guidelines is essential for at-risk individuals.
Importantly, while EPA proved effective, mixed omega-3 products lacking substantial evidence for heart health did not provide the same benefits. We believe adding EPA-only formulations to cardiovascular prevention guidelines is essential for at-risk individuals.
Read More
9
8-HEPE benefits cholesterol management
We explored how 8-hydroxyeicosapentaenoic acid (8-HEPE), derived from Pacific krill, could improve cholesterol levels in mice commonly used for dyslipidemia studies.
Over eighteen weeks, mice on a high-cholesterol diet receiving 8-HEPE showed significantly higher levels of good HDL cholesterol, alongside lower levels of bad LDL cholesterol and liver triglycerides.
This suggests that 8-HEPE may enhance lipid profiles and liver health by influencing certain genes in macrophages. While promising, further research is needed to confirm these benefits in humans.
Over eighteen weeks, mice on a high-cholesterol diet receiving 8-HEPE showed significantly higher levels of good HDL cholesterol, alongside lower levels of bad LDL cholesterol and liver triglycerides.
This suggests that 8-HEPE may enhance lipid profiles and liver health by influencing certain genes in macrophages. While promising, further research is needed to confirm these benefits in humans.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 16 Reviews
7.9
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Family health boost
321 people found this helpful
Excellent! Omega 3 lowers cholesterol levels, reduces inflammation and improves skin and hair quality. The taste of fish is noticeable, but the quality and composition are excellent, as is the dosage. Although the price has increased due to dollar surges, prioritising health is essential. It's suitable for the whole family, with ample packaging for everyone.
Read More
9
Lower bad cholesterol
19 people found this helpful
Beneficial Supplement: Helps lower bad cholesterol levels. This jar contains an excellent concentration of EPA and DHA – the reason for taking Omega 3.
Read More
9
Great omega choice
3 people found this helpful
The best omega 3 I've tried. This one outperforms others, leaving no fishy taste. It also lowers cholesterol effectively. A brilliant product!
Read More
9
Supports cholesterol levels
2 people found this helpful
The quality of this omega is exceptional. The ingredients are top-notch, and they've greatly improved my overall wellbeing. The packaging is very convenient, and this product supports the heart, restores cholesterol levels, and reduces inflammation. Its neutral taste makes it easy to take. I recommend it to everyone.
Read More
9
Skin health improvement
1 people found this helpful
This product features 500mg capsules, making them easier to swallow. There's no fishy taste, just olive oil with rosemary. I take a prophylactic dose of 1000mg daily, which has significantly improved my skin's hydration and elasticity. It helps with eczema too, healing it quickly. I highly recommend Omega-3 from Life Extension.
Read More
Frequently Asked Questions
7.5
Effective Omega 3
1 people found this helpful
The effect of this product was apparent within the first week of taking it. With a high concentration of Omega 3 at 2000mg, including 700mg of EPA and 500mg of DHA, I find it unmatched in similar products. Just a note for those on a 2000 calorie diet, as the calories are high. The quality of the packaging also protects the product from light damage.
6
Cholesterol level change
6 people found this helpful
Excellent! It has a slight smell, and the capsules are large and black. After finishing the course, I felt a noticeable change. I didn't have an analysis done, but I purchased it specifically for my high cholesterol levels. I take it after breakfast and exercise 2-3 times a week. My doctor advised against excessive omega intake, emphasising moderation.
9
Lowers cholesterol effectively
Effective in lowering cholesterol.
7.5
Supports heart function
The quality of this omega is outstanding. It supports heart function, restores cholesterol levels, removes inflammation, and improves joints, skin, hair and nails. The taste is neutral, and it's easy to take. It also benefits cognitive health. I recommend it to everyone.
7.5
Increases good cholesterol
We always buy this omega, and tests have shown a clear increase in good cholesterol levels.
9
Supports cholesterol levels
2 people found this helpful
The quality of this omega is exceptional. The ingredients are top-notch, and they've greatly improved my overall wellbeing. The packaging is very convenient, and this product supports the heart, restores cholesterol levels, and reduces inflammation. Its neutral taste makes it easy to take. I recommend it to everyone.
9
Skin health improvement
1 people found this helpful
This product features 500mg capsules, making them easier to swallow. There's no fishy taste, just olive oil with rosemary. I take a prophylactic dose of 1000mg daily, which has significantly improved my skin's hydration and elasticity. It helps with eczema too, healing it quickly. I highly recommend Omega-3 from Life Extension.
7.5
Family health boost
321 people found this helpful
Excellent! Omega 3 lowers cholesterol levels, reduces inflammation and improves skin and hair quality. The taste of fish is noticeable, but the quality and composition are excellent, as is the dosage. Although the price has increased due to dollar surges, prioritising health is essential. It's suitable for the whole family, with ample packaging for everyone.
7.5
Effective dietary supplement
1 people found this helpful
I struggle with bad cholesterol, and Omega-3 is part of my supplement regimen aimed at lowering it. This dietary supplement is exceptional, with very clean oil and an optimal dosage, even for three capsules a day.
9
We aimed to understand how Antarctic krill oil (ESKO) affects cholesterol levels, particularly in relation to obesity. Through our study involving mice, we observed that ESKO helped reduce oxidative stress and improve cholesterol metabolism.
While a high-fat diet usually worsens cholesterol levels, ESKO demonstrated a protective effect by reducing fat accumulation and promoting better metabolic health. This suggests that krill oil could be a promising option for managing high cholesterol and obesity-related issues.
While a high-fat diet usually worsens cholesterol levels, ESKO demonstrated a protective effect by reducing fat accumulation and promoting better metabolic health. This suggests that krill oil could be a promising option for managing high cholesterol and obesity-related issues.
8
We investigated how fish oil (FO) affects liver fat accumulation in response to a high-cholesterol (CH) diet using KK mice. The study included groups that received either safflower oil or varying amounts of fish oil along with cholesterol over eight weeks.
The results showed that the group with the highest fish oil intake had significantly lower liver triglyceride and cholesterol levels compared to the group with only safflower oil. This suggests that fish oil may indeed help prevent fat accumulation in the liver linked to high cholesterol, reducing the risk of fatty liver disease.
The results showed that the group with the highest fish oil intake had significantly lower liver triglyceride and cholesterol levels compared to the group with only safflower oil. This suggests that fish oil may indeed help prevent fat accumulation in the liver linked to high cholesterol, reducing the risk of fatty liver disease.
9
We conducted a comprehensive trial to understand how different types of omega-3 fatty acids affect cholesterol levels and inflammation in adults struggling with high cholesterol.
Over 12 weeks, participants took various doses of omega-3s, including EPA and DHA, revealing notable benefits. Those receiving higher doses of EPA and DHA saw their triglycerides drop significantly—by up to 15.78%—compared to controls.
Interestingly, ALA supplementation did not lead to improvements in cholesterol or inflammation status, highlighting the superior role of EPA and DHA in managing these health issues.
Over 12 weeks, participants took various doses of omega-3s, including EPA and DHA, revealing notable benefits. Those receiving higher doses of EPA and DHA saw their triglycerides drop significantly—by up to 15.78%—compared to controls.
Interestingly, ALA supplementation did not lead to improvements in cholesterol or inflammation status, highlighting the superior role of EPA and DHA in managing these health issues.
9
We analyzed the effects of icosapent ethyl, a form of Omega 3 fish oil, on patients with high triglycerides and cardiovascular issues. The REDUCE-IT trial involved over 8,000 statin-treated patients and demonstrated that icosapent ethyl significantly reduced both the first and total ischemic events, which include serious heart conditions like heart attacks and strokes.
This means that those at risk saw meaningful benefits from this treatment. Overall, we found that icosapent ethyl could be a valuable option for improving heart health in patients struggling with high cholesterol and triglycerides.
This means that those at risk saw meaningful benefits from this treatment. Overall, we found that icosapent ethyl could be a valuable option for improving heart health in patients struggling with high cholesterol and triglycerides.
References
- Choi JH, Park SE, Kim S. Antarctic Krill Oil Supplementation Attenuates Hypercholesterolemia, Fatty Liver, and Oxidative Stress in Diet-Induced Obese Mice. Nutrients. 2024;16. 10.3390/nu16213614
- Hirako S, Kim H, Iizuka Y, Matsumoto A. Fish oil consumption prevents hepatic lipid accumulation induced by high-cholesterol feeding in obese KK mice. Biomed Res. 2024;45:33. 10.2220/biomedres.45.33
- Mjaatveit M, Oldernes H, Gudbrandsen OA. Effects of diets containing fish oils or fish oil concentrates with high cetoleic acid content on the circulating cholesterol concentration in rodents. A systematic review and meta-analysis. Br J Nutr. 2024;131:606. 10.1017/S0007114523002118
- Zhang C, Wang X, Sun S, Fu Y, Wu Y, et al. Fat-1 expression alleviates atherosclerosis in transgenic rabbits. J Cell Mol Med. 2022;26:1306. 10.1111/jcmm.17188
- Sugimoto K, Hosomi R, Shimono T, Kanda S, Nishiyama T, et al. Comparison of the Cholesterol-Lowering Effect of Scallop Oil Prepared from the Internal Organs of the Japanese Giant Scallop (Patinopecten yessoensis), Fish Oil, and Krill Oil in Obese Type II Diabetic KK-A Mice. J Oleo Sci. 2021;70:965. 10.5650/jos.ess21032
- Jaca A, Durão S, Harbron J. Omega-3 fatty acids for the primary and secondary prevention of cardiovascular disease. S Afr Med J. 2020;110:1158. 10.7196/SAMJ.2020.v110i12.14730
- Trivedi K, Le V, Nelson JR. The case for adding eicosapentaenoic acid (icosapent ethyl) to the ABCs of cardiovascular disease prevention. Postgrad Med. 2021;133:28. 10.1080/00325481.2020.1783937
- Saito M, Ishida N, Yamada H, Ibi M, Hirose M. 8-HEPE-Concentrated Materials from Pacific Krill Improve Plasma Cholesterol Levels and Hepatic Steatosis in High Cholesterol Diet-Fed Low-Density Lipoprotein (LDL) Receptor-Deficient Mice. Biol Pharm Bull. 2020;43:919. 10.1248/bpb.b20-00162
- Llop-Talaveron J, Badía-Tahull M, Lozano-Andreu T, Rigo-Bonnin R, Virgili-Casas N, et al. Phytosterolemia and γ-glutamyl transferase in adults with parenteral nutrition: Fish versus vegetal lipids: A randomized clinical trial. Nutrition. 2020;70:110587. 10.1016/j.nut.2019.110587
- Antona ME, Ramos C, Stranges A, Monteiro AF, Gonzales Chaves MM, et al. Fish oil diet effects on alveolar bone loss, in hypercholesterolemic rats. Arch Oral Biol. 2020;109:104553. 10.1016/j.archoralbio.2019.104553
- Zhou Q, Zhang Z, Wang P, Zhang B, Chen C, et al. EPA+DHA, but not ALA, Improved Lipids and Inflammation Status in Hypercholesterolemic Adults: A Randomized, Double-Blind, Placebo-Controlled Trial. Mol Nutr Food Res. 2019;63:e1801157. 10.1002/mnfr.201801157
- Bhatt DL, Steg PG, Miller M, Brinton EA, Jacobson TA, et al. Effects of Icosapent Ethyl on Total Ischemic Events: From REDUCE-IT. J Am Coll Cardiol. 2019;73:2791. 10.1016/j.jacc.2019.02.032
- Preston Mason R. New Insights into Mechanisms of Action for Omega-3 Fatty Acids in Atherothrombotic Cardiovascular Disease. Curr Atheroscler Rep. 2019;21:2. 10.1007/s11883-019-0762-1
- Vikøren LA, Drotningsvik A, Bergseth MT, Mjøs SA, Austgulen MH, et al. Intake of Baked Cod Fillet Resulted in Lower Serum Cholesterol and Higher Long Chain -3 PUFA Concentrations in Serum and Tissues in Hypercholesterolemic Obese Zucker fa/fa Rats. Nutrients. 2018;10. 10.3390/nu10070840
- Blom WAM, Koppenol WP, Hiemstra H, Stojakovic T, Scharnagl H, et al. A low-fat spread with added plant sterols and fish omega-3 fatty acids lowers serum triglyceride and LDL-cholesterol concentrations in individuals with modest hypercholesterolaemia and hypertriglyceridaemia. Eur J Nutr. 2019;58:1615. 10.1007/s00394-018-1706-1
- Shen J, Rastogi R, Guan L, Li F, Du H, et al. Omega-3 fatty acid supplement reduces activation of NADPH oxidase in intracranial atherosclerosis stenosis. Neurol Res. 2018;40:499. 10.1080/01616412.2018.1451290
